Week 3 of the 2025 NFL season closes out with a Monday Night Football matchup between the Detroit Lions and the Baltimore Ravens. The game takes place in Baltimore at M&T Bank Stadium, where the Ravens are coming off a 41-17 win over the Cleveland Browns. Meanwhile, the Lions look to bounce back from a 27-13 road loss to the Green Bay Packers. Many pundits had this matchup circled as a potential Super Bowl LX matchup.
The Ravens and Lions are both 1-1 heading into Week 3. Baltimore opened its season with a 41-40 loss on the road to the Buffalo Bills in a game they were leading by 15 points late in the fourth quarter. Detroit’s first game of 2025 was a 52-21 shellacking of the Chicago Bears at home.
The Ravens and Lions have met seven times. Baltimore holds a 6-1 record in the series. Detroit’s only win came in 2005 when they beat Baltimore 35-17 in Detroit. The Ravens have won the past five meetings between the clubs, with the most recent win coming in 2023, when Baltimore won 38-6 at home.
Before we lay out the odds, preview, and prediction for the Detroit Lions vs. Baltimore Ravens in Week 2 2025 NFL action, check out our NFL betting odds and Super Bowl LX odds for 2026.
| Teams |  |  |  |
|---|---|---|---|
| Detroit Lions | +203 | +205 | +215 |
| Baltimore Ravens | -245 | -245 | -255 |
| Detroit Lions +4.5 | -110 | -110 | -110 |
| Baltimore Ravens -4.5 | -110 | -110 | -110 |
| Over 52.5 | -115 | -110 | -110 |
| Under 52.5 | -105 | -110 | -110 |
The Detroit Lions enter Week 3 of the 2025 NFL season with the No. 3 scoring offense in the league with an average of 32.5 points per game. Meanwhile, the defense ranks 21st, giving up 24.0 points per outing.
Jared Goff is among the NFL leaders in yards (559), completions (54), average (8.3 yards), and yards per game (279.5), while leading the league in completion percentage at 80.6. He has six touchdown passes and one interception.
The Lions need to take advantage of the questionable Ravens defense, who are likely to be without star linebacker Kyle Van Noy, who suffered a hamstring injury against the Browns. Even with Van Noy in the lineup, the Ravens D hasn’t been great. Goff needs to attack in the air, where the Ravens are the second-worst team in the NFL, giving up an average of 298.5 yards per game.
Offense is what is going to win this game, and with the Lions averaging 267 yards in the air per game, they have a chance to hang with Baltimore if they can establish the passing game early.
We have seen two different versions of the Lions so far this year, and we still don’t know which version of the team is the true version. This game could go a long way to showing what to expect from Detroit for the rest of 2025.
The Baltimore Ravens have the highest scoring offense in the NFL so far this year, with an average of 40.5 points per game. The defense ranks 25th, surrendering an average of 29.0 points per matchup.
Lamar Jackson is having a decent season in the passing department, completing 68.8 percent of his passes (33 for 48) for 434 yards. He has thrown for six touchdowns and zero interceptions. Jackson, who is also known for his running ability, has eight carries for 83 yards and one rushing TD. Jackson has a 24-2 career record against NFC teams with a 7-2 record on Monday Night Football. His touchdown-to-interception ratio on MNF is 22-0. Jackson is very hard to beat on Monday Night.
Derrick Henry had a very good game in Week 1, but he came back to earth in Game 2, where he averaged 2.1 yards per carry on 11 attempts for 23 yards total. In Week 1, Henry picked up 169 yards on 18 carries for an average of 9.4 yards while scoring twice. The Ravens need a bounce-back performance from Henry against Detroit.
The Ravens’ defense collapsed in Game 1 against the Bills but looked better against the Browns. However, they will have their work cut out for them against Goff’s active passing game. If Goff can establish control early, the Ravens’ defense could be the weak spot that costs them on Monday Night Football.
Lamar Jackson and the Baltimore Ravens have been dominant against NFC teams and don’t look for that to change on Monday night at home.
The betting pick is for the Ravens to beat the Detroit Lions on Monday Night Football.
There will be a lot of offense in this game as both teams are aggressive and high scoring. So, while the over looks very high for this game, expect these teams to rack up points.
The betting pick is for the Detroit Lions and Baltimore Ravens to hit the over on Monday Night Football.
See below the top Las Vegas betting sites where you can wager online and choose the best one for you:
