The 2025 NCAA football season is winding down. This weekend, Week 13 games take place. In the early national game on ABC, the Missouri Tigers travel to Norman to face the Oklahoma Sooners in an SEC matchup.
The Tigers bring a 7-3 overall record and a 3-3 SEC mark into the contest. Missouri started the season strong, winning its first five games. However, when the Tigers matched up against ranked teams Alabama, Vanderbilt, and Texas A&M, it fell short, losing those matchups. The squad is coming off a 49-27 win over Mississippi State at home. Missouri is in eighth place in the SEC.
The Sooners are the No. 11 ranked team in the nation heading into Week 13. Oklahoma has a 8-2 overall record to go along with a 4-2 mark in the SEC. The Sooners won their first five contests of the 2025 campaign. The team’s first loss came in mid-October to Texas. They also fell to Ole Miss later that month. Oklahoma bounced back from those losses with back-to-back wins over Tennessee and Alabama, both ranked clubs. The Sooners are in fifth place in the conference.
Oklahoma leads the all-time series against Missouri 67-25-5. Missouri won the most recent meeting of these teams, 30-23 at home in November 2024.
| Teams |  |  |  |
|---|---|---|---|
| Missouri Tigers | +249 | +260 | +238 |
| Oklahoma Sooners | -305 | -320 | -285 |
| Missouri +7.5 | -110 | -110 | -110 |
| Oklahoma -7.5 | -110 | -110 | -110 |
| Over 42 Points | -110 | -110 | -110 |
| Under 42 Points | -110 | -110 | -110 |
With the 2025 NCAA football season winding down, be sure to check out our NCAAF playoff odds, as well as our betting picks to win the NCAA Football National Championship in 2025.
The Missouri Tigers will not make the College Football Playoffs this year, but the team has the chance to play the role of spoiler against Oklahoma this week. For some, that might be sufficient motivation, but you can get on the fact that it will be enough to get the Tigers ready for Saturday’s road game.
The Tigers have a two-pronged running attack that will test the aggressive Oklahoma defense. Ahmad Hardy is the No. 1 running back in college football with 1,346 yards on 197 attempts. His average yards per carry is No. 1 in the SEC at 6.8. The other back the team has is Jamal Roberts, who is the No. 11 rusher in the SEC with 583 yards on 92 carries. Roberts averages 6.3 yards per carry, which is fourth-best in the conference.
On the other side of the offense. If Missouri can get the time and space to throw passes, Donovan Olugbode could be the player to watch, as he has shown he can be a game-changer.
Missouri needs to hang onto the ball if the team hopes to win. They need to limit turnovers and come out ahead on the turnover margin.
The Oklahoma Sooners finish the 2025 NCAAF season with home games against Missouri and LSU. If the team wins those matchups, they are likely to secure a spot in the College Football Playoffs.
Oklahoma had 212 yards of total offense against Alabama (138 passing, 74 rushing). In their previous game against Tennessee, that number was 351 total yards (159 passing, 192 rushing). The Sooners need the offense to deliver something like they did against the Crimson Tide when they face the Tigers on Saturday.
Oklahoma’s best bet is to follow the blueprint set by Texas A&M when the Aggies beat Missouri 38-17 in early November. In that game, Texas A&M went for 464 total yards of offense, picking up 221 in the air on 29 passing attempts and 243 on the ground on 39 rushing attempts.
The Sooners’ defense needs to be careful not to be over-aggressive on the rushing side of the game. If they give Missouri time, space, and vision, Saturday could be a bad day for Oklahoma’s D.
With two big wins in its last two games, the Oklahoma Sooners will not let up in Week 13 against the Missouri Tigers. Expect the team to do whatever it can to keep its College Football Playoff hopes alive this weekend at home.
The betting pick is that Oklahoma will beat Missouri in Week 13.
Oklahoma is the No. 1 team in the SEC in points per game allowed, giving up a paltry 14.8. Last week, the Sooners held Alabama to 21 points, and in their previous win, they allowed Tennessee to score 27. Missouri does not have the offensive firepower of either of those clubs. On the offensive side of the ball, the Sooners average 28.3 points per game, which puts them in the bottom half of the conference’s points-per-game rankings.
The betting pick is that Oklahoma and Missouri will combine for fewer than 42 points.
See below the best online betting sites. You can read our comprehensive reviews to help determine the best option for your 2025 NCAA football betting.
